5-Chloro-2-thiophenecarboxylic acid

2-chlorothiophene-5-carboxylic acid is a yellow to brown solid with a unique sulfur odor. It is only slightly soluble in water at room temperature, but can dissolve in organic solvents.

Purpose:

2-chlorothiophene-5-carboxylic acid is often used as an intermediate in organic synthesis, especially in the preparation of thiophene compounds, which has important application value. It can also be used as a dye, photosensitizer, fluorescent analysis reagent, etc.

Manufacturing method:

There are many methods for preparing 2-chlorothiophene-5-carboxylic acid, and one common method is to react 2-chlorothiophene with methanol in the presence of sodium hydroxide to produce 2-chlorothiophene-5-methanol. Then, under the action of an acid catalyst, the methanol group is converted to a carboxyl group to obtain 2-chlorothiophene-5-methyl acid.

Security information:

2-chlorothiophene-5-carboxylic acid is irritating and should be avoided from contact with skin, eyes, and mucous membranes. During operation, personal protective equipment such as chemical protective gloves, glasses, and face shields should be worn to ensure sufficient ventilation conditions. Attention should be paid to avoiding contact with strong oxidants and acidic substances to prevent accidental reactions. During storage and transportation, it is necessary to avoid high temperatures and sources of fire.