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Silane-PEG-MAL (Silane Polyethylene Glycol Maleimide) — Focus on PEG derivatives

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Silane-PEG-MAL (silane polyethylene glycol maleimide) is a type of silane coupling agent (PEG derivative), which can react with inorganic materials (glass, metal, SiO2) and the like.


By using silane coupling agents, a "molecular bridge" can be built between the interfaces of inorganic and organic substances, connecting two materials with very different properties together to improve the performance of composite materials and increase the bonding strength.


This property of silane coupling agents was first used in glass fiber reinforced plastics (FRP) as a surface treatment agent for glass fiber, which greatly improved the mechanical properties, electrical properties and anti-aging properties of FRP.


Maleimide can form a stable thioether bond with thiol at pH 6.5-7.5. Silane coupling agents connected by PEG have good water solubility.


Silane PEG maleimide (Silane-PEG-MAL) can be used to modify proteins, peptides and other active group materials or small molecules.


Maleimide (-MAL) Maleimide and thiol can easily form a stable thioether bond at pH 6.5-7.5.


Polyethylene glycol can increase solubility and stability, reduce the immunogenicity of peptides and proteins, and it can also inhibit the nonspecific binding of charged molecules on the modified surface.



English name: Silane-PEG-Mal

English alias:

Silane-PEG-Maleimide

Molecular weight: 600, 1k, 2k, 3.4k, 5k, 10k (customizable)

Product purity:

≥95%

Product use:

Applied in medical research, drug release, nanotechnology and new materials research, cell culture. And ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.

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