DBCO-PEG-SH (dibenzocyclooctyne-polyethylene glycol-thiol) — Focus on PEG derivatives

DBCO-PEG-SH (dibenzocyclooctyne-polyethylene glycol-thiol) undergoes chemical reactions without any metal catalysts.

The strain-promoted 1,3-dipolar cycloaddition of cyclooctyne and azide, also known as the copper-free click reaction, is a bioorthogonal reaction that allows the conjugation of two molecules in aqueous solution.

DBCO-PEG derivatives exhibit fast kinetics and stability in aqueous buffers.

DBCO reagents can be used to label azide-modified biomolecules without the need for toxic copper catalysts.

PEGylation can increase the solubility and stability of peptides and proteins and reduce their immunogenicity.

It can also inhibit the nonspecific binding of charged molecules to the modified surface.

English name: DBCO-PEG-SH

Alias:

Dibenzocycolctyne-PEG-Thiol

DBCO-PEG-Thiol

Molecular weight: 400, 500, 600, 1k, 2k, 3.4k, 5k (customizable)

Product purity:

≥95%

Product use:

Applied in medical research, drug release, nanotechnology and new materials research, cell culture. And ligand research, peptide synthesis support, grafted polymer compounds, new materials and polyethylene glycol modified functional coatings and other active compounds.