N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-D-Glutamic Acid

N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-D-Glutamic Acid - Names and Identifiers

Name	N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-D-Glutamic Acid
Synonyms	Fmoc-D-Glu-OH Fmoc-D-glutamic acid Fmoc-D-glutamic acid N-FMOC-D-GLUTAMIC ACID N-Fmoc-D-glutamic acid N-Fmoc-D-glutamic AcidFmoc-D-Glu-OH (9H-Fluoren-9-yl)MethOxy]Carbonyl D-Glu-OH N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-glutamic Acid N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-D-Glutamic Acid (((9H-fluoren-9-yl)methoxy)carbonyl)-D-glutamic acid N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-D-GLUTAMIC ACID (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanedioic acid (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanedioic acid
CAS	104091-09-0
InChI	InChI=1/C20H19NO6/c22-18(23)10-9-17(19(24)25)21-20(26)27-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16-17H,9-11H2,(H,21,26)(H,22,23)(H,24,25)/t17-/m1/s1

N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-D-Glutamic Acid - Physico-chemical Properties

Molecular Formula	C20H19NO6
Molar Mass	369.37
Density	1.366±0.06 g/cm3(Predicted)
Boling Point	635.8±50.0 °C(Predicted)
Flash Point	338.311°C
Vapor Presure	0mmHg at 25°C
Appearance	powder to crystal
Color	White to Almost white
pKa	3.72±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	19 ° (C=1, DMF)

N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-D-Glutamic Acid - Introduction

Fmoc-D-Glutamic acid is a chemical reagent, which is widely used in peptide synthesis and protein analysis in chemical synthesis.

The nature of Fmoc-D-glutamic acid is a white crystalline solid with a molecular weight of 374.4. It is an unnatural amino acid, the D isomer of glutamic acid. Fmoc-D-glutamic acid has good solubility and can be dissolved in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane.

The main use of Fmoc-D-glutamic acid is the introduction of amino acid units in polypeptide synthesis. It can be combined with other amino acids into a polypeptide chain by methods such as solid phase synthesis or liquid phase synthesis. The synthesis of polypeptide chains is an important tool for studying the function and structure of proteins. In addition, Fmoc-D-glutamic acid can also be used for drug candidate screening and drug delivery system construction in drug development.

The production method of Fmoc-D-glutamic acid is usually obtained by chemical synthesis. Specifically, Fmoc-D-glutamic acid can be synthesized by binding a D-form isomer of glutamic acid to an Fmoc protecting group. The synthetic steps include reaction, purification and crystallization, etc.

When using Fmoc-D-glutamic acid, it is necessary to pay attention to its safety. It is a chemical reagent, so laboratory safety procedures should be followed. Avoid contact with skin and eyes, wear protective gloves and goggles if necessary. At the same time, store it in a dry, cool place to avoid contact with oxidants and combustibles. If inhaled or ingested, seek medical assistance immediately.