3,4-Dihydroxypyridine

3,4-Dihydroxypyridine - Names and Identifiers

Name	3,4-Dihydroxypyridine
Synonyms	BRN 0110211 3,4-Pyridinediol 3,4-pyridinediol pyridin-3,4-diol Pyridine-3,4-diol 3,4-DIHYDROXYPYRIDINE 3,4-Dihydroxypyridine 3-hydroxypyridin-4(1H)-one 5-21-12-00105 (Beilstein Handbook Reference)
CAS	10182-48-6
EINECS	1806241-263-5
InChI	InChI=1/C5H5NO2/c7-4-1-2-6-3-5(4)8/h1-3,8H,(H,6,7)

3,4-Dihydroxypyridine - Physico-chemical Properties

Molecular Formula	C5H5NO2
Molar Mass	111.1
Density	1.397±0.06 g/cm3(Predicted)
Boling Point	509.8±30.0 °C(Predicted)
Flash Point	117.4°C
Vapor Presure	0.000895mmHg at 25°C
pKa	8.02±0.18(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.593

3,4-Dihydroxypyridine - Introduction

3,4-Dihydroxypyridine, also known as 3,4-dihydroxypyridinone, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 3,4-Dihydroxypyridine is white to light yellow crystal or powder.
-Solubility: It is soluble in common organic solvents such as water, ethanol and ether.
-Chemical properties: 3,4-Dihydroxypyridine is a basic compound that releases hydrogen under acidic conditions.

Use:
-Chemical reagent: 3,4-dihydroxypyridine can be used as a reagent and catalyst in organic synthesis. It can be used for oxidation reaction, carbonylation reaction and dehydration reaction of alcohol.
-Drug: Because 3,4-dihydroxypyridine has biological activity, it can be used as a raw material for drugs to synthesize a variety of compounds with antibacterial, anti-inflammatory and anti-tumor activities.

Preparation Method:
- 3,4-dihydroxypyridine can be prepared by oxidation of pyridine. A common method of preparation is the oxidation of pyridine to 3,4-dihydroxypyridine with hydrogen peroxide or other oxidizing agents.

Safety Information:
- 3,4-dihydroxypyridine is relatively stable at room temperature, but dangerous reactions may occur at high temperatures or in contact with strong oxidants. Attention should be paid to fire and explosion-proof measures.
-Use in accordance with laboratory safety practices to avoid contact with skin, eyes and inhalation of dust. In the case of accidental contact, rinse immediately with plenty of water and seek medical assistance.
- 3,4-Dihydroxypyridine is a chemical and should be stored in a dry, well-ventilated place, away from ignition and flammable materials.