(S)-1-Boc-2-hydroxymethylpiperazine

(S)-1-Boc-2-hydroxymethylpiperazine - Names and Identifiers

Name	(S)-1-Boc-2-hydroxymethylpiperazine
Synonyms	(S)-1-Boc-2-hydroxymethylpiperazine (S)-1-N-BOC-2-HYDROXYMETHYLPIPERAZINE (2S)-2-(Hydroxymethyl)piperazine, N1-BOC protected (S)-tert-butyl 2-(hydroxyMethyl)piperazin-1-carboxylate tert-butyl (S)-2-(hydroxymethyl)piperazine-1-carboxylate tert-butyl (2S)-2-(hydroxymethyl)piperazine-1-carboxylate (S)-2-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (s)-2-(hydroxymethyl)piperazine-1-carboxylic acid tert-butyl ester 1-PIPERAZINECARBOXYLIC ACID, 2-(HYDROXYMETHYL)-, 1,1-DIMETHYLETHYL ESTER, (2S)- tert-Butyl (2S)-2-(hydroxymethyl)piperazine-1-carboxylate, (2S)-1-(tert-Butoxycarbonyl)-2-(hydroxymethyl)piperazine
CAS	1030377-21-9

(S)-1-Boc-2-hydroxymethylpiperazine - Physico-chemical Properties

Molecular Formula	C10H20N2O3
Molar Mass	216.28
Density	1.085
Boling Point	324℃
Flash Point	150℃
pKa	14.97±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Sensitive	Irritant
MDL	MFCD07772093

(S)-1-Boc-2-hydroxymethylpiperazine - Introduction

(S)-1-BOC-2-hydroxymethylpiperazine is an organic compound with the chemical formula C12H22N2O3.

Nature:
(S)-1-BOC-2-hydroxymethyl piperazine is a white solid, non-volatile at room temperature, soluble in common organic solvents, such as ethanol and dimethylformamide. This compound has the property of being stable to air and moisture, but long-term contact with water should be avoided.

Use:
(S)-1-BOC-2-hydroxymethyl piperazine is widely used in chemical synthesis. It is mainly used for intermediates and protecting groups in organic synthesis reactions. It can be used to synthesize bioactive molecules and drugs, such as anti-cancer drugs and analgesics.

Preparation Method:
A common method for preparing (S)-1-BOC-2-hydroxymethylpiperazine is obtained by the condensation reaction of N-hydroxypiperazine with BOC-Alanil. Specific synthetic methods can be found in the organic synthetic chemistry literature or literature databases.

Safety Information:
When using or handling (S)-1-BOC-2-hydroxymethyl piperazine, the following safety precautions should be taken:
1. avoid prolonged contact with skin and eyes, use should wear chemical protective gloves and eye protection equipment.
2. in the use of the process should maintain good ventilation conditions, avoid inhalation of aerosols or dust.
3. storage should be sealed stored in a dry, cool place, and away from the fire and flammable materials.
4. If exposed or inhaled, rinse immediately with plenty of water and seek medical attention.