fmoc-3,5-diiodo-L-tyrosine CAS 103213-31-6

fmoc-3,5-diiodo-L-tyrosine - Names and Identifiers

Name	fmoc-3,5-diiodo-L-tyrosine
Synonyms	Fmoc-Tyr(3,5-I2)-OH FMOC-TYR(3,5-I2)-OH Fmoc-Tyr(3,5-DiI)-OH FMOC-TYR(3,5-DI-I)-OH FMOC-L-TYR(3,5-I2)-OH Fmoc-Tyr(3,5-di-I)-OH FMOC-3,5-DIIODO-TYR-OH Fmoc-3,5-diiodo-Tyr-OH FMOC-3,5-DIIODO-TYROSINE FMOC-3,5-DIIODO-L-TYROSINE fmoc-3,5-diiodo-L-tyrosine N-9-Fluorenylmethoxycarbonyl-3,5-diiodo-L-tyrosine NALPHA-9-Fluorenylmethoxycarbonyl-3,5-diiodo-L-tyrosine N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3,5-diiodo-L-tyrosine
CAS	103213-31-6
InChI	InChI=1/C24H19I2NO5/c25-19-9-13(10-20(26)22(19)28)11-21(23(29)30)27-24(31)32-12-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-10,18,21,28H,11-12H2,(H,27,31)(H,29,30)/t21-/m0/s1

fmoc-3,5-diiodo-L-tyrosine - Physico-chemical Properties

Molecular Formula	C24H19I2NO5
Molar Mass	655.22
Density	1.893±0.06 g/cm3(Predicted)
Boling Point	687.3±55.0 °C(Predicted)
Flash Point	369.5°C
Vapor Presure	7.8E-20mmHg at 25°C
Appearance	White powder
Color	White
BRN	9022736
pKa	2.78±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,2-8°C
Sensitive	Light Sensitive
Refractive Index	1.716
MDL	MFCD00063330

fmoc-3,5-diiodo-L-tyrosine - Risk and Safety

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
FLUKA BRAND F CODES	8
Hazard Class	IRRITANT

fmoc-3,5-diiodo-L-tyrosine - Introduction

Fmoc-3, 5-diiodo-L-tyrosine is an organic compound that is commonly used as a protecting group in solid phase synthesis (peptide synthesis) and can be used to synthesize complex polypeptides. Its chemical formula is C22H15I2NO4.

Fmoc-3, the main properties of 5-diiodo-L-tyrosine are as follows:
-Appearance: White or off-white solid
-Solubility: Soluble in some organic solvents (such as dichloromethane, methanol), insoluble in water
-Flammability: It may be combustible, it is recommended to avoid contact with fire sources during storage

Fmoc-3, the primary use of 5-diiodo-L-tyrosine is as a protecting group for polypeptides. By introducing it into the polypeptide synthesis process, a non-specific reaction can be prevented from occurring to protect a specific group.
It can also prepare polypeptides by solid-phase synthesis, which is a common method for synthesizing a large number of polypeptides. During synthesis, Fmoc-3, 5-diiodo-L-tyrosine can be gradually deprotected, allowing for continuous elongation of the polypeptide chain.

Fmoc-3, the preparation method of 5-diiodo-L-tyrosine is complicated and includes multiple steps. A common method of preparation is by reacting L-tyrosine with diiodomethane and then with Fmoc-carbamylene to give the final product.

Regarding safety information, Fmoc-3, 5-Diiodo-L-tyrosine is a chemical that is potentially dangerous. During use, it is necessary to follow laboratory safety procedures and wear appropriate protective equipment, such as laboratory gloves and protective glasses. At the same time, it should be stored in a dry, cool place, avoid contact with oxidants, fire sources, etc. If you come into contact with this compound, rinse immediately with water and seek medical help.