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(R)-tert-butyl 2-methylpiperazine-1-carboxylate hydrochloride

Names and IdentifiersName(R)-tert-butyl 2-methylpiperazine-1-carboxylate hydrochlorideSynonyms(

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Names and Identifiers

Name(R)-tert-butyl 2-methylpiperazine-1-carboxylate hydrochloride
Synonyms(R)-1-N-BOC-2-METHYL PIPERAZINE-HCl
(R)-1-Boc-2-Methylpiperazine hydrochloride
(R)-1-N-Boc-2-methyl Piperazine Hydrochloride
(R)-tert-butyl 2-Methylpiperazine-1-carboxylate hydrochloride
(R)-tert-butyl 2-methylpiperazine-1-carboxylate hydrochloride
tert-Butyl (R)-2-methylpiperazine-1-carboxylate hydrochloride
(2R)-2-Methyl-1-piperazinecarboxylic acid tert-butyl ester hydrochloride
CAS1000853-53-1
InChIInChI=1S/C10H20N2O2.ClH/c1-8-7-11-5-6-12(8)9(13)14-10(2,3)4;/h8,11H,5-7H2,1-4H3;1H/t8-;/m1./s1

Physico-chemical Properties

Molecular FormulaC10H21ClN2O2
Molar Mass236.74
Storage Conditionunder inert gas (nitrogen or Argon) at 2-8°C

Introduction

(R)-BOC-2-methylpiperazine hydrochloride is an organic compound with the formula C10H21ClN2O2, which belongs to the hydrochloride salt form.

Nature:
(R)-BOC-2-methylpiperazine hydrochloride is a white crystalline solid, stable at ambient temperature, soluble in water and organic solvents. It has good thermal stability and chemical stability.

Use:
(R) - BOC-2-methylpiperazine hydrochloride is mainly used as a protective group in organic synthesis. It is often used as a protective group for amino acids and in peptide synthesis. It can protect amino or hydroxyl groups to prevent unnecessary changes during the reaction. After synthesis, the protective groups can be removed under appropriate conditions.

Preparation Method:
Preparation of (R)-BOC-2-methylpiperazine hydrochloride can be obtained by reacting (R)-BOC-2-methylpiperazine with hydrochloric acid. (R)-BOC-2-methylpiperazine was first dissolved in a suitable solvent, and then dilute hydrochloric acid solution was slowly added dropwise, resulting in a white precipitate. Next, the precipitate is collected, washed, and dried to obtain (R)-BOC-2-methylpiperazine hydrochloride.

Safety Information:
(R)-BOC-2-methylpiperazine hydrochloride is generally a low-toxic substance under routine operation. However, during use, you should still follow the safety procedures of the chemical laboratory, such as wearing appropriate personal protective equipment, maintaining good ventilation, avoiding contact with skin and eyes, and avoiding inhalation or ingestion. In case of accidental contact, rinse thoroughly with plenty of water immediately and seek medical help. At the same time, the material should be properly stored and disposed of to avoid contact with oxidants and other substances, and the waste should be properly disposed.

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