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2-Amino-5-formylthiazole CAS 1003-61-8

2-Amino-5-formylthiazole - Names and IdentifiersName2-Amino-5-formylthiazoleSynonyms2-AMINO-5-F

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2-Amino-5-formylthiazole - Names and Identifiers

Name2-Amino-5-formylthiazole
Synonyms2-AMINO-5-FORMYLTHIAZOLE
2-Amino-5-formylthiazole
2-Amino-5-formyl-1,3-thiazole
2-Aminothiazole-5-carbadehyde
2-AMINOTHIAZOLE-5-CARBALDEHYDE
2-AMINOTHIAZOLE-5-CARBOXALDEHYDE
2-amino-1,3-thiazole-5-carbaldehyde
CAS1003-61-8
InChIInChI=1/C4H4N2OS/c5-4-6-1-3(2-7)8-4/h1-2H,(H2,5,6)
InChIKeyHZKMBJCDAXLMDN-UHFFFAOYSA-N

2-Amino-5-formylthiazole - Physico-chemical Properties

Molecular FormulaC4H4N2OS
Molar Mass128.15
Density1.488±0.06 g/cm3(Predicted)
Melting Point122-132°C
Boling Point316.3±15.0 °C(Predicted)
Flash Point145.1°C
Vapor Presure0.000413mmHg at 25°C
pKa3.16±0.10(Predicted)
Storage ConditionKeep in dark place,Inert atmosphere,Room temperature
SensitiveAir Sensitive
Refractive Index1.712
MDLMFCD02179570
Physical and Chemical PropertiesStorage Conditions: Keep Cold
sensitivity: Air Sensitive
WGK Germany:3

2-Amino-5-formylthiazole - Risk and Safety

Risk CodesR22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin.
R43 - May cause sensitization by skin contact
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37 - Wear suitable protective clothing and gloves.
WGK Germany3
HS Code29349990
Hazard NoteIrritant/Keep Cold
Hazard ClassIRRITANT

2-Amino-5-formylthiazole - Introduction

2-Amino-5-formylthiazole (2-Amino-5-formylthiazole) is an organic compound with the chemical formula C4H4N2OS.

Nature:
- 2-Amino -5-aldehyde thiazole is a colorless to slightly yellow crystalline or powdery solid.
-It is slightly soluble in water and soluble in organic solvents such as alcohols, ethers and chlorinated hydrocarbons.
-The compound is weakly acidic.

Use:
- 2-amino -5-aldehyde thiazole is widely used in organic synthesis as a synthetic intermediate.
-It can be used to synthesize other compounds, such as organic fluorescent dyes, biologically active molecules, etc.
-It can also be used as a ligand in coordination chemistry to participate in metal ion coordination reactions.

Preparation Method:
The preparation method of -2-amino -5-aldehyde thiazole is mainly obtained by N-deprotection or N-defunctional reaction of thiazole.
-A commonly used synthesis method is to react thiazole with N-methyl-N-nitroglycine ester, and deprotection under appropriate conditions to obtain 2-amino-5-aldehydyl thiazole.

Safety Information:
- 2-amino -5-aldehyde thiazole compounds are less toxic and corrosive to human body.
-During operation and storage, avoid contact with harmful substances such as strong oxidants and strong acids.
-When using this compound, wear protective gloves and protective glasses to avoid inhaling its dust or touching your skin.
-In case of accidental contact or inhalation, flush with plenty of water and seek medical help.

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