Biochemical functions: Biopterin has two isomers (D- and L-biopterin). We sell only L-Biopterin. The
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Package: 1g,5g,10g,1kg..or according to requirements. Storage: in a dry and ventilated warehouse; keep away from sunshine and moisture.
| Name | 6-Biopterin |
| Synonyms | 6-Biopterin L-Biopterin D-erythro-Biopterin L-Biopterin(6-Biopterin) 2-amino-6-(1,2-dihydroxypropyl)pteridin-4(1H)-one 2-amino-7-(1,2-dihydroxypropyl)pteridin-4(1H)-one 2-amino-6-(1,2-dihydroxypropyl)-1H-pteridin-4-one 2-Amino-4-hydroxy-6-(1,2-dihydroxypropyl)pteridine 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]pteridin-4(1H)-one 2-Amino-6-[(1S,2R)-1,2-dihydroxypropyl]pteridin-4(1H)-one 2-Amino-6-[(1S,2R)-1,2-dihydroxypropyl]pteridine-4(3H)-one [S-(R*,S*)]-2-amino-6-(1,2-dihydroxypropyl)-1H-pteridin-4-one L-Biopterin,2-Amino-4-hydroxy-6-(1,2-dihydroxypropyl)pteridine (1R,2S)-Biopterin, 2-Amino-4-hydroxy-6-(1,2-dihydroxypropyl)pteridine, L-erythro-6-(1,2-Dihydroxypropyl)pterin |
| CAS | 22150-76-1 |
| EINECS | 244-807-8 |
| InChI | InChI=1/C9H11N5O3/c1-3(15)6(16)4-2-11-5-7(12-4)13-9(10)14-8(5)17/h2-3,6,15-16H,1H3,(H3,10,12,13,14,17) |
| Molecular Formula | C9H11N5O3 |
| Molar Mass | 237.22 |
| Density | 1.3472 (rough estimate) |
| Melting Point | >210°C dec. |
| Boling Point | 379.74°C (rough estimate) |
| Specific Rotation(α) | D24 -50° (c = 0.4 in 0.1N HCl); D24 -26° (c = 0.92 in 0.1N NaOH) |
| Flash Point | 295.2°C |
| Solubility | Bioptein is very slightly soluble in water. The solubility of biopterin is about 0.01 |
| Vapor Presure | 1.4E-13mmHg at 25°C |
| Appearance | Crystalline solid |
| Color | White to Light Yellow |
| Merck | 13,1229 |
| BRN | 87860 |
| pKa | 13.18±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Stability | Hygroscopic |
| Refractive Index | 1.7610 (estimate) |
| MDL | MFCD00036787 |
| Use | 6-Biopterin is an oxidation product from the melanogenesis regulating cofactor (6R)5,6,7,8 tetrahydrobiopterin (6-BH4). In vitro, 6-Biopterin is cytotoxic to melanocytes. However, in vivo, 6-Biopterin is rapidly and sequentially reduced back to 6-GH4 |
| In vitro study | 6-biopterin is extremely cytotoxic to human melanocytes under in vitro conditions. Thioredoxin reductase has the capacity to reduce 6-biopterin to q-BH2 where further reduction to 6-BH4 follows via dihydropteridine reductase or reduced glutathione. (6R)5,6,7,8 tetrahydrobiopterin undergoes redox-cycling by its oxidation to quinonoid dihydrobiopterin and to 6-biopterin through consecutive two electron oxidation reactions. |
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