Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate

Molecular Formula: C14H13NO4S Molecular Weight: 291.32 CAS Registry Number: 161798-01-2 Density: 1.3352- (3-aldehyde 4-hydroxyphenyl) -4-methylthiazole-5-carboxylic acid ethyl ester, also known as Ugi key intermediate, has the following properties and uses:

Name: Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate

CAS: 161798-01-2

Appearance: yellowish powder

Assay: ≥99%

Capacity: 100mt/year

Min.package: 1gram

Application: Febuxostat intermediate

Standard: enterprise export

nature:

Appearance: White crystalline powder

Soluble: soluble in some organic solvents such as methanol, ethanol, and dimethylformamide

Stability: Stable, not easily decomposed

Purpose:

Manufacturing method:

Ethyl 2- (3-aldehyde-4-hydroxyphenyl) -4-methylthiazole-5-carboxylate can be synthesized through a multi-step reaction. A common method is to react 3-hydroxy-4-methylbenzaldehyde with ethyl methoxyacetic acid, methyl mercaptan, and dimethylformamide, and obtain the target product after acid catalysis and deprotection reaction.

Security information:

2- (3-aldehyde 4-hydroxyphenyl) -4-methylthiazole-5-carboxylic acid ethyl ester is a chemical with certain toxicity. Please pay attention to safety when using it.

When stored, it should be sealed and kept away from sources of fire and oxidants.

When preparing and using, relevant safety operating procedures and laboratory regulations should be followed, and personal protective equipment such as laboratory gloves and protective goggles should be used.