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(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol tetraacetate

2-chloro-5- (2,3,4,6-tetra-O-acetyl - β - D-glucopyranos-1-yl) -4 '- ethoxydiphenylmethane is an org

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Content

2-chloro-5- (2,3,4,6-tetra-O-acetyl - β - D-glucopyranos-1-yl) -4 '- ethoxydiphenylmethane is an organic compound. The following is an introduction to the properties, uses, preparation methods, and safety information of the compound:

nature:

-Appearance: 2-chloro-5- (2,3,4,6-tetra-O-acetyl - β - D-glucopyranos-1-yl) -4 '- ethoxydiphenylmethane is a white crystalline solid.

-Solubility: It can dissolve in organic solvents such as dichloromethane and ethanol, but has poor solubility in water.

Purpose:

Manufacturing method:

The preparation of 2-chloro-5- (2,3,4,6-tetra-O-acetyl - β - D-glucopyranos-1-yl) -4 '- ethoxydiphenylmethane generally requires multiple reactions. A common preparation method is to first react 2,3,4,6-tetra-O-acetyl - β - D-glucopyranose with benzyl magnesium bromide to obtain the corresponding benzyl alcohol, which is then subjected to chlorination reaction with 2-chloro-5- (4 '- ethoxybenzyl) phenylacetone.

Security information:

-2-chloro-5- (2,3,4,6-tetra-O-acetyl - β - D-glucopyranos-1-yl) -4 '- ethoxydiphenylmethane should be stored in a dry, cool, and well ventilated place, away from sources of fire and oxidants.

-During the operation, appropriate personal protective equipment such as gloves, goggles, and protective clothing should be worn.

-When handling or disposing of this compound, local regulations and environmental protection requirements should be followed.

Name(2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate
SynonymsAcetyl Dapagliflozin
Dapagliflozin Impurity 41
Dapagliflozin Tetracetate
Dapagliflozin Intermediate 4
(1S)-1,5-Anhydro-1-C-[4-Chloro-3-[(4-Ethoxyphenyl)Methyl]Phenyl]-D-Glucitol Tetraacetate
D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)Methyl]phenyl]-, 2,3,4,6-tetraacetate, (1S)-
(2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-[4-chloro-3-(4-ethoxybenzyl)phenyl]tetrahydropyran-3,4,5-triyl Triacetate
(2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-(4-chloro-3-(4-ethoxybenzyl)phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate
(2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-(4-chloro-3-(4-ethoxybenzyl)-phenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate
4,(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol tetraacetate5,6,7-Tetrahydro-1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
CAS461432-25-7
EINECS930-010-9
Molecular FormulaC29H33ClO10
Molar Mass577.02
Density1.29±0.1 g/cm3(Predicted)
Boling Point626.8±55.0 °C(Predicted)
Vapor Presure0Pa at 25℃
AppearancePowder
Storage ConditionSealed in dry,Room Temperature
SensitiveIRRITANT

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