1H-Indazole-6-carboxylic acid, 5-amino-, methyl ester CAS 1000373-79-4

1H-Indazole-6-carboxylic acid, 5-amino-, methyl ester - Names and Identifiers

1H-Indazole-6-carboxylic acid, 5-amino-, methyl ester - Physico-chemical Properties

1H-Indazole-6-carboxylic acid, 5-amino-, methyl ester - Introduction

Nature:
Methyl 5-amino-[1H] indazole-6-carboxylate is a colorless to light yellow solid with high thermal and chemical stability. It can be dissolved in common organic solvents at room temperature, such as alcohols, ketones and esters.

Usage:
5-Amino - [1H] indole-6-carboxylic acid methyl ester is often used as an intermediate in organic synthesis. It can serve as an important reagent for synthesizing biologically active molecules, and can also be used as a precursor for dyes in the dye industry.

Preparation Method:
A common preparation method is to react 5-aminoindazole-6-carboxylic acid with methanol to produce methyl 5-amino-[1H] indazole-6-carboxylate. During the reaction, an acid catalyst such as sulfuric acid or thionyl chloride may be used to promote the reaction.

Safety Information:
Methyl 5-amino-[1H] indazole-6-carboxylate is generally relatively safe under proper handling. However, as a chemical, it still has some potential dangers. During operation, necessary protective measures should be taken, such as wearing protective glasses, gloves and laboratory coats. At the same time, it should be operated in a well-ventilated laboratory environment to avoid inhalation or contact with skin. In the event of exposure or accident, appropriate first aid measures should be taken immediately and medical assistance should be sought.