5-Bromo-3-methyl-2(1H)-pyrazinone CAS 100047-56-1

5-Bromo-3-methyl-2(1H)-pyrazinone - Names and Identifiers

5-Bromo-3-methyl-2(1H)-pyrazinone - Physico-chemical Properties

5-Bromo-3-methyl-2(1H)-pyrazinone - Introduction

Nature:
2-Hydroxy-3-methyl-5-bromopyrazine is a yellow solid. It is soluble in alcohol and ketone solvents, slightly soluble in water.
Usage:
2-hydroxy-3-methyl-5-bromopyrazine is commonly used in the field of organic synthesis. It can be used as an intermediate in the synthesis of pyrazine derivatives, such as dyes. In addition, it can also be used as a catalyst, reducing agent, and reagent in protective group reactions.

Preparation Method:
2-Hydroxy-3-methyl-5-bromopyrazine is usually prepared by the following steps:
1. reaction of pyrazine with sodium hypobromite to generate 3-bromopyrazine.
2. Using ethanol as solvent, it reacts with cresol under alkaline conditions to form 2-hydroxy-3-bromopyrazine.
3. Finally, 2-hydroxy-3-bromopyrazine was reduced with sodium aluminohydride under hydrogen atmosphere to obtain 2-hydroxy-3-methyl-5-bromopyrazine.

Safety Information:
2-hydroxy-3-methyl-5-bromopyrazine is an organic compound, which should be used safely. It may irritate the eyes, skin and respiratory system. During the operation, you should wear appropriate protective clothing and gloves, avoid contact with skin and eyes, and pay attention to protect the respiratory tract. Avoid fire and high temperatures during storage and handling. If accidental contact, should promptly rinse with plenty of water, and consult a doctor.