1-(4-Pyridyl)-piperazine CAS 1008-91-9

1-(4-Pyridyl)-piperazine - Names and Identifiers

Name	1-(4-Pyridyl)-piperazine
Synonyms	RARECHEM AH CK 0194 4-PIPERAZINOPYRIDINE LABOTEST-BB LT00233138 1-(4-PYRIDYL)PIPERAZINE 1-(4-Pyridyl)piperazine pyridine-4-sulfonic acid 1-(4-Pyridyl)-piperazine 4-(1-Piperazino)pyridine 1-PYRIDIN-4-YL-PIPERAZINE 1-(4-PYRIDINYL)PIPERAZINE 1-(pyridin-4-yl)piperazine
CAS	1008-91-9
EINECS	213-764-7
InChI	InChI=1/C5H5NO3S/c7-10(8,9)5-1-3-6-4-2-5/h1-4H,(H,7,8,9)

1-(4-Pyridyl)-piperazine - Physico-chemical Properties

Molecular Formula	C9H13N3
Molar Mass	163.22
Density	1.081±0.06 g/cm3(Predicted)
Melting Point	137-141 °C
Boling Point	195-200°C 0,3mm
Flash Point	195-200°C/0.3mm
Water Solubility	Soluble in water.
Solubility	soluble in Methanol
Appearance	Crystalline powder
Color	White to Light yellow
BRN	609705
pKa	10.73±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Sensitive	Air Sensitive
Refractive Index	1.576
MDL	MFCD00040745

1-(4-Pyridyl)-piperazine - Risk and Safety

Risk Codes	R34 - Causes burns R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36 - Wear suitable protective clothing. S37/38/39 -
UN IDs	UN 3259 8/PG 2
WGK Germany	3
FLUKA BRAND F CODES	10-34
HS Code	29335990
Hazard Note	Irritant
Hazard Class	8
Packing Group	II

1-(4-Pyridyl)-piperazine - Introduction

1-(4-Pyridine) piperazine, also known as 4-piperazinylpyridine, is an organic compound.

Nature:
1-(4-Pyridine) piperazine is a white crystalline solid with weak basic properties. It is insoluble in water at room temperature, but soluble in organic solvents such as ethanol and dimethyl sulfoxide. Its molecular formula is C11H14N2 and its molecular weight is 174.24g/mol.

Use:
1-(4-Pyridine) piperazine has important applications in the field of medicine. It can be used as a pharmaceutical intermediate for the synthesis of a variety of bioactive compounds, such as antihypertensive drugs, antidepressants and antitumor drugs. In addition, it can also be used as a catalyst in organic synthesis.

Preparation Method:
1-(4-Pyridine) piperazine is usually prepared by nucleophilic substitution reaction of pyridine and 1,4-dibromobutane under basic conditions. During the preparation process, attention should be paid to safe operation, avoid contact with skin and inhalation of gas.

Safety Information:
1-(4-pyridine) piperazine is generally safe under normal use conditions, but the following safety precautions should be paid attention to during preparation and operation:
-Avoid inhaling dust or vapors and wear suitable protective masks and glasses.
-Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water and seek medical advice.
-Follow laboratory safety regulations during operation, use appropriate protective gloves and laboratory ventilation equipment.
-When storing and transporting, it should be stored in a sealed container, away from fire and oxidizing agents.

The information provided above is for reference only. Please read the relevant literature and safety materials carefully before specific use, and follow the correct experimental operation procedures and safety measures.